本帖最後由 goodcat1111 於 2009-4-30 14:47 編輯
作者：Allison Gandey
出處：WebMD醫學新聞
April 15, 2009 — 一項運動計畫證實在降低偏頭痛頻率以及改善生活品質上是有潛力的；即使運動可能誘發部分偏頭痛，但新的研究結果顯示，有氧運動介入可能耐受性良好、甚至能改善預後。
主要作者來自瑞典哥德堡Cephalea頭痛中心的Emma Varkey博士在一項新聞稿中表示，當還不清楚偏頭痛病患的最佳運動量時，我們目前所評估的運動計畫可以進一步地測試，且與藥物及非藥物治療比較，看運動是否可以改善偏頭痛。
這項研究發表在4月號的頭痛期刊上。
【生活品質顯著改善】
研究者針對瑞典頭痛診所的26位病患進行研究。該運動計畫，主要是室內騎腳踏車，每週進行3次，為期12週。該運動計畫被設計來改善未經訓練偏頭痛病患的最大氧氣攝取量。
該研究團隊評估偏頭痛狀態、氧氣攝取、不良反應與生活品質。他們發現偏頭痛狀態並未惡化，且事實上，在治療的最後一個月，相較於治療前，偏頭痛發作次數、每個月偏頭痛發作天數、平均頭痛強度、使用治療頭痛藥物數目顯著下降。
研究團隊也發現運動計畫，最大氧氣攝取量從32.9 ml/kg/min增加到36.2 ml/kg/min（P= 0.044），沒有病患發生不良反應，但是其中有一位病患在一次訓練剛開始時發生有前兆的偏頭痛。
以偏頭痛特定生活品質問卷，研究團隊報告，完成運動計畫的病患，生活品質顯著改善。
【研究結果是令人激勵的 但仍非最終結論】
研究團隊指出，相較於沒有偏頭痛者，有頭痛與偏頭痛者典型地運動量較少。罹患偏頭痛的病患經常避免運動，造成他們有氧耐受度與柔軟度較差。
研究團隊寫到，偏頭痛狀態與生活品質的正面結果是令人感到激勵的，但因為這不是一項雙盲研究，且沒有控制組，所以並不是最終結論。針對偏頭痛病患運動，設計良好的研究是必須的。
研究者們表示沒有相關資金上的往來。
Exercise Program Reduces Migraine
By Allison Gandey
Medscape Medical News
April 15, 2009 — An exercise program has shown promise in decreasing the frequency of migraine and improving quality of life, report researchers. Even though physical activity can trigger migraine in some, new study results suggest the aerobic intervention can be well tolerated and even improve outcomes.
"While the optimal amount of exercise for patients with migraine remains unknown, our evaluated program can now be tested further and compared with pharmacological and nonpharmacological treatments to see if exercise can prevent migraine," lead author Emma Varkey, PhD, from the Cephalea Headache Center, in Gothenburg, Sweden, said in a news release.
The study is published in the April issue of Headache.
Significant Improvement in Quality of Life
Researchers studied 26 patients from the Swedish headache clinic. The exercise program, based on indoor cycling, was performed 3 times a week for 12 weeks. The program was developed to improve maximum oxygen uptake in untrained patients with migraine.
The research team evaluated migraine status, oxygen uptake, adverse effects, and quality of life. They found there was no deterioration in migraine status, and in fact, during the last month of treatment, there was a significant decrease in the number of migraine attacks, the number of days with migraine per month, mean headache intensity, and amount of headache medication used compared with baseline.
Investigators also found that after the exercise program, maximum oxygen uptake increased from 32.9 mL/kg/minute to 36.2 mL/kg/minute (P = .044). None of the patients reported adverse effects. But a patient experienced a migraine with aura that started immediately after training on 1 occasion.
As measured by the Migraine-Specific Quality-of-Life questionnaire, researchers report a significant improvement in patients completing the exercise program.
Results Encouraging, but Inconclusive
Individuals with headache and migraine typically are less physically active than those without headache, the investigators point out. Patients with migraine often avoid exercise, resulting in less aerobic endurance and flexibility.
"The positive results reported in migraine status and quality of life are encouraging but inconclusive, since this was not a blinded study and there was no control group," the researchers write. "Well-designed studies of exercise in patients with migraine are imperative."
The researchers have disclosed no relevant financial relationships.
Headache. 2009;49:563-570. |
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